Medications


Benralizumab injection

What is this medicine?

BENRALIZUMAB (BEN ra LIZ oo mab) is used to help treat severe asthma. It should be used in combination with other asthma treatments.

How should I use this medicine?

This medicine is for injection under the skin. It may be administered by a healthcare professional in a hospital or clinic setting or at home. If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used injectors, needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls

  • signs and symptoms of infection like fever or chills; cough; sore throat

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

  • headache

  • pain, redness, or irritation at the site where injected

What may interact with this medicine?

Interactions are not expected.

What if I miss a dose?

It is important not to miss your dose. Call your doctor of health care professional if you are unable to keep an appointment. If you give yourself the medicine and you miss a dose, call your doctor or health care professional for advice.

Where should I keep my medicine?

Keep out of the reach of children.

Store unopened syringes or injectors in a refrigerator between 2 to 8 degrees C (36 to 46 degrees F). Keep in the original container until ready for use. Protect from light. Do not freeze. Do not shake. Prior to use, remove the syringe or injector from the refrigerator and use after 30 minutes at room temperature. Throw away any unused medicine after the expiration date on the label.

If needed, the unopened syringe or injector may be stored at room temperature up to 25 degrees C (77 degrees F) for a maximum of 14 days. Once removed from the refrigerator and brought to room temperature, the syringe or autoinjector must be used within 14 days or discarded.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • parasitic (helminth) infection

  • an unusual or allergic reaction to benralizumab, hamster proteins, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your healthcare professional for regular checks on your progress. NEVER use this medicine for an acute asthma attack. Tell your healthcare professional if your symptoms do not start to get better or if they get worse.

Do not stop taking your other asthma medicines unless instructed to do so by your doctor or health care professional.


NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2019 Elsevier
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